Fig. 1 · Structure
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Mito-LND
OXPHOS Inhibitor
Mito-LND (Mito-Lonidamine) is an orally active inhibitor of oxidative phosphorylation (OXPHOS) that targets mitochondria. By disrupting mitochondrial bioenergetics, Mito-LND promotes the production of reactive oxygen species and induces autophagic cell death, particularly in lung cancer cells. This compound is valuable for research focused on cancer cell metabolism and the modulation of mitochondrial pathways in therapeutic contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2361564-49-8 |
| Applications | OXPHOS Inhibitor |
| Formula | C43H45BrCl2N3OP |
| Molecular Weight | 801.62 |
| Synonyms | Mito-Lonidamine |
| SMILES | O=C(NCCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C4=NN(CC5=CC=C(Cl)C=C5Cl)C6=C4C=CC=C6.[Br-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.