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Mizoribine 5'-monophosphate

IMPDH Inhibitor

Mizoribine 5'-monophosphate is a potent inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH). It exhibits Ki values against IMPDH of Trypanosoma brucei, Bacillus subtilis, and Oceanobacillus iheyensis at 3.3, 72, and 157 nM, respectively. This compound is valuable in research applications related to anti-trypanosomiasis and immunosuppression, providing significant insights into biological pathways and therapeutic potentials.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	62025-48-3
Applications	IMPDH Inhibitor
Formula	C₉H₁₄N₃O₉P
Molecular Weight	339.20
Synonyms	MZR-P
SMILES	O[C@H]1[C@@H](O)[C@H](N2C(O)=C(C(N)=O)N=C2)O[C@@H]1COP(O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.