Fig. 1 · Structure

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MK-0963

Cat. No. A69143 CAS 103497-68-3

5α-reductase Inhibitor

MK-0963 is a steroidal inhibitor of 5α-reductase, effectively reducing serum dihydrotestosterone (DHT) levels in a dose-dependent manner. This compound is valuable for studying dihydrotestosterone-related conditions, including benign prostatic hyperplasia (BPH). Its ability to modulate DHT concentrations makes MK-0963 a significant tool in research aimed at understanding and treating disorders associated with androgen metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 103497-68-3
Applications 5α-reductase Inhibitor
Formula C23H35NO2
Molecular Weight 357.53
Synonyms L 654066
SMILES
C[C@@]12[C@](CC[C@@H]2C(CC(C)C)=O)([H])[C@@]3([H])[C@]([C@@]4([C@@](NC(C=C4)=O)([H])CC3)C)([H])CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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