MK-1029

Catalog No.: A63143
DP2 Antagonist
MK-1029 is a potent DP2 antagonist that selectively inhibits the D-type prostaglandin receptor. This compound exhibits significant activity in modulating inflammatory responses and bronchoconstriction, making it a valuable tool for investigating respiratory diseases such as asthma. Its ability to block DP2 signaling pathways aids in understanding the underlying mechanisms of chronic airway diseases and evaluating potential therapeutic strategies.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMK-1029 is a potent DP2 antagonist that selectively inhibits the D-type prostaglandin receptor. This compound exhibits significant activity in modulating inflammatory responses and bronchoconstriction, making it a valuable tool for investigating respiratory diseases such as asthma. Its ability to block DP2 signaling pathways aids in understanding the underlying mechanisms of chronic airway diseases and evaluating potential therapeutic strategies.
Product Information
Catalog NumA63143
FormulaC17H20FNO5S
Molecular Weight369.41
CAS Number1242273-04-6
SMILESO=C(OCC)CC1=C(CC[C@H](OS(=O)(C)=O)C2)N2C3=C1C=CC=C3F
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