Fig. 1 · Structure
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MK 386
Cat. No.
A69129
CAS
158493-17-5
5 alpha Reductase Inhibitor
MK 386 is a selective inhibitor of 5-alpha reductase type I, which plays a critical role in the metabolism of testosterone into dihydrotestosterone (DHT). By inhibiting this enzyme, MK 386 is utilized in research focused on prostate cancer treatment and hormone-related disorders. Its specificity for 5-alpha reductase I makes it a valuable tool for studying the effects of DHT modulation on cellular and molecular pathways associated with prostate cancer progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 158493-17-5 |
| Applications | 5 alpha Reductase Inhibitor |
| Formula | C28H49NO |
| Molecular Weight | 415.69 |
| Synonyms | L-733692 |
| SMILES | C[C@@]12[C@]3([H])[C@]([C@@H](C)C[C@@]1([H])N(C(CC2)=O)C)([H])[C@@]4([H])[C@@](C)([C@]([C@H](C)CCCC(C)C)([H])CC4)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.