Fig. 1 · Structure
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MK 436
Antitrypanosomal Agent
MK 436 is an antitrypanosomal agent with demonstrated efficacy against Trypanosoma cruzi, the causative agent of Chagas disease. This metabolite, which can be isolated from canine urine, is of interest for research applications focused on the treatment and understanding of Chagas disease and related parasitic infections. Its potency and specificity make it a valuable compound for studies in parasitology and drug development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 33450-08-7 |
| Applications | Antitrypanosomal Agent |
| Formula | C11H14N4O3 |
| Molecular Weight | 250.25 |
| Synonyms | MK-0436 |
| SMILES | O=[N+](C1=CN=C(C2=NOC3CCCCC23)N1C)[O-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.