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Biological Activity
MK-5046 is a novel BRS-3 agonist, binds to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.5 mL | 112.52 mL | 225.04 mL |
| 0.5 mM | 4.5 mL | 22.5 mL | 45.01 mL |
| 1 mM | 2.25 mL | 11.25 mL | 22.5 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
*The above data is based on the productmolecular weight 444.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21214 |
|---|---|
| Actions | Agonist |
| CAS No. | 1022152-70-0 |
| Formula | C20H18F6N4O |
| M. Wt | 444.37 |
| Purity | >98% |
| Synonyms | MK5046, MK 5046 |
| SMILES | O[[email protected]](CC1=NC(CC2(C(F)(F)F)CC2)=CN1)(C(F)(F)F)C3=CC=C(N4C=CC=N4)C=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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