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MK-6892

GPR109A agonist

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Catalog No. A12982

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MK-6892 5mg A12982-5
$280.00
MK-6892 10mg A12982-10
$420.00
MK-6892 50mg A12982-50
$950.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MK-6892 is a potent, selective, and full agonist for the high affinity nicotinic acid (NA) receptor GPR109A.K i and GTPγS EC 50 of MK-6892 on the Human GPR109A is 4 nM and 16 nM, respectively.

MK-6892

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Chemical Information

Catalog Num A12982
Actions Agonist
M. Wt 386.4
Formula C19H22N4O5
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 917910-45-3
Synonyms MK6892, MK 6892
SMILES OC(C=C1)=CN=C1C2=NOC(CC(C)(C)C(NC3=C(C(O)=O)CCCC3)=O)=N2

Biological Activity

Description
MK-6892 is a potent, selective, and full agonist for the high affinity nicotinic acid (NA) receptor GPR109A.K i and GTPγS EC 50 of MK-6892 on the Human GPR109A is 4 nM and 16 nM, respectively.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.88 mL 129.4 mL 258.8mL
0.5 mM 5.18 mL 25.88 mL 51.76 mL
1 mM 2.59 mL 12.94 mL 25.88 mL
5 mM 0.52 mL 2.59 mL 5.18 mL

*The above data is based on the productmolecular weight 386.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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