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Biological Activity
MK-6892 is a potent, selective, and full agonist for the high affinity nicotinic acid (NA) receptor GPR109A.K i and GTPγS EC 50 of MK-6892 on the Human GPR109A is 4 nM and 16 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.88 mL | 129.4 mL | 258.8 mL |
| 0.5 mM | 5.18 mL | 25.88 mL | 51.76 mL |
| 1 mM | 2.59 mL | 12.94 mL | 25.88 mL |
| 5 mM | 0.52 mL | 2.59 mL | 5.18 mL |
*The above data is based on the productmolecular weight 386.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12982 |
|---|---|
| Actions | Agonist |
| CAS No. | 917910-45-3 |
| Formula | C19H22N4O5 |
| M. Wt | 386.4 |
| Purity | >98% |
| Synonyms | MK6892, MK 6892 |
| SMILES | OC(C=C1)=CN=C1C2=NOC(CC(C)(C)C(NC3=C(C(O)=O)CCCC3)=O)=N2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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