MK-7246 S enantiomer

Catalog No.: A63445
Prostaglandin Receptor Antagonist
MK-7246 S enantiomer is a selective antagonist of the prostaglandin receptor CRTH2. While it exhibits reduced activity compared to its R enantiomer, it is still valuable for investigating the role of CRTH2 in various biological processes. This compound is primarily used in research applications focused on asthma, allergic responses, and other inflammation-related studies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMK-7246 S enantiomer is a selective antagonist of the prostaglandin receptor CRTH2. While it exhibits reduced activity compared to its R enantiomer, it is still valuable for investigating the role of CRTH2 in various biological processes. This compound is primarily used in research applications focused on asthma, allergic responses, and other inflammation-related studies.
Product Information
Catalog NumA63445
FormulaC21H21FN2O4S
Molecular Weight416.47
CAS Number2310135-53-4
SMILESCN([C@H]1CCC2=C(C3=CC=CC=C3N2C1)CC(O)=O)S(=O)(C4=CC=C(C=C4)F)=O
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