Fig. 1 · Structure

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MK-8325

HCV NS5A Inhibitor

MK-8325 is an orally active inhibitor of the hepatitis C virus non-structural protein 5A (NS5A). It demonstrates a selective target profile with minimal activity against the hERG channel at concentrations of 30 mM. This compound is suitable for use in research related to hepatitis C virus infection and may aid in the investigation of HCV pathogenesis and therapy.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1334312-52-5
Applications HCV NS5A Inhibitor
Formula C43H52F2N8O6Si
Molecular Weight 843.01
SMILES
O=C(OC)N[C@@H](C(C)C)C(N1C[Si](C)(C)C[C@H]1C2=NC3=CC=C4C=C(C5=CC=C(C6=CN=C([C@H]7N(C([C@H](C(C)C)NC(OC)=O)=O)CC(F)(F)C7)N6)C=C5)C=CC4=C3N2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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