Fig. 1 · Structure
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MKK7-COV-9
Covalent MKK7 Inhibitor
MKK7-COV-9 is a selective covalent inhibitor of MKK7, targeting a specific protein-protein interaction to modulate its activity. This compound effectively blocks primary B cell activation in response to lipopolysaccharide (LPS), demonstrating an EC50 value of 4.98 μM. MKK7-COV-9 serves as a valuable tool for investigating the role of MKK7 in cellular signaling pathways and immune response research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2283355-59-7 |
| Applications | Covalent MKK7 Inhibitor |
| Formula | C18H16N4O2 |
| Molecular Weight | 320.35 |
| SMILES | O=C(NC)C1=CC(NC(C=C)=O)=CC(C2=NNC3=C2C=CC=C3)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.