Fig. 1 · Structure
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ML-10
Apoptosis Probe
ML-10 is a small molecule apoptosis probe that selectively targets apoptotic cells. Its unique structural features allow for radiolabeling with 18F isotopes, making it suitable for positron emission tomography (PET) imaging studies of apoptosis. ML-10 is preferentially taken up by cells undergoing apoptosis, while remaining excluded from live or necrotic cells, and its accumulation is associated with key apoptotic markers, including caspase activation, Annexin-V binding, and changes in mitochondrial membrane potential. This compound facilitates research into apoptosis and provides insights into cell death mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1216897-16-3 |
| Applications | Apoptosis Probe |
| Formula | C9H15FO4 |
| Molecular Weight | 206.21 |
| SMILES | O=C(O)C(C)(CCCCCF)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.