Fig. 1 · Structure
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ML188
3CLpro Inhibitor
ML188 is a selective non-covalent inhibitor of the SARS-CoV-2 3CLpro enzyme, demonstrating an IC50 of 1.5 μM. This compound exhibits significant antiviral activity, making it a valuable tool for research into the mechanisms of viral replication and potential therapeutic applications against coronavirus infections. It serves as a key probe for studying 3CLpro inhibition and advancing the development of antiviral strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1417700-13-0 |
| Applications | 3CLpro Inhibitor |
| Formula | C26H31N3O3 |
| Molecular Weight | 433.54 |
| SMILES | O=C(NC(C)(C)C)[C@@H](C1=CN=CC=C1)N(C(C=C2)=CC=C2C(C)(C)C)C(C3=CC=CO3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.