ML216

Catalog No.: A21754

BLM helicase inhibitor

ML216

ML216 Chemical Structure

CAS NO. 1430213-30-1

ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 μM and 0.97 μM for BLMfull-length and BLM636-1298, respectively.

Availability: In stock

Package Price Qty
5 mg
$59.00
10 mg
$102.00
50 mg
$304.00
100 mg
$607.00
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Biological Activity

ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 μM and 0.97 μM for BLMfull-length and BLM636-1298, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.09 mL 130.44 mL 260.88 mL
0.5 mM 5.22 mL 26.09 mL 52.18 mL
1 mM 2.61 mL 13.04 mL 26.09 mL
5 mM 0.52 mL 2.61 mL 5.22 mL

*The above data is based on the productmolecular weight 383.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21754
Actions Inhibitor
M. Wt 383.32
Formula C15H9F4N5OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1430213-30-1
Synonyms CID-49852229, CID49852229, CID 49852229; ML-216, ML 216
SMILES O=C(NC1=CC=C(F)C(C(F)(F)F)=C1)NC2=NN=C(S2)C3=CC=NC=C3

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