Fig. 1 · Structure
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ML241 hydrochloride
p97 Inhibitor
ML241 hydrochloride is a selective inhibitor of the p97 ATPase, demonstrating potent activity with an IC50 of 100 nM. This compound plays a crucial role in investigating the biological functions of p97 in cellular processes such as protein degradation and membrane fusion. It is valuable in various research applications related to cancer biology, neurodegenerative diseases, and protein homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2070015-13-1 |
| Applications | p97 Inhibitor |
| Formula | C23H25ClN4O |
| Molecular Weight | 408.92 |
| SMILES | Cl[H].C1(N2C3=CC=CC=C3OCC2)=NC(NCC4=CC=CC=C4)=C5CCCCC5=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.