Fig. 1 · Structure
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ML247
Cat. No.
A75185
CAS
1222374-44-8
Acid α-glucosidase Molecule Chaperone
ML247 is a selective small molecule chaperone that targets acid α-glucosidase, facilitating proper protein folding and function. This compound enhances enzyme activity and stability, making it a valuable tool for investigating metabolic disorders, particularly Pompe disease. Its role in improving enzyme efficacy underscores its potential in research applications focused on lysosomal storage diseases and enzyme replacement therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1222374-44-8 |
| Applications | Acid α-glucosidase Molecule Chaperone |
| Formula | C18H24N4O3S |
| Molecular Weight | 376.47 |
| SMILES | COC(C(OC)=C1)=CC=C1CN(C2=C3CN(CCC)CN2)C(NC3=O)=S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.