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ML314

NTR1 agonist

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Catalog No. A13570

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ML314 5mg A13570-5
€332.50
ML314 10mg A13570-10
€570.00
ML314 25mg A13570-25
€1,140.00
ML314 50mg A13570-50
€1,900.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ML-314 is a brain penetrant nonpeptidic β-arrestin biased ggonist of the neurotensin NTR1 receptor, which exhibits full agonist behavior against NTR1 (EC50 = 2.0 μM) in the primary assay and selectivity against NTR2.

ML314

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Chemical Information

Catalog Num A13570
Actions Agonist
M. Wt 420.22
Formula C24H28N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1448895-09-7
Synonyms ML 314, ML-314
SMILES COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5

Biological Activity

Description
ML-314 is a brain penetrant nonpeptidic β-arrestin biased ggonist of the neurotensin NTR1 receptor, which exhibits full agonist behavior against NTR1 (EC50 = 2.0 μM) in the primary assay and selectivity against NTR2.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.8 mL 118.99 mL 237.97mL
0.5 mM 4.76 mL 23.8 mL 47.59 mL
1 mM 2.38 mL 11.9 mL 23.8 mL
5 mM 0.48 mL 2.38 mL 4.76 mL

*The above data is based on the productmolecular weight 420.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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