ML355

Catalog No.: A18349

12-Lipoxygenase (12-LOX) inhibitor

ML355

ML355 Chemical Structure

CAS NO. 1532593-30-8

ML355 is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 μM, shows excellent selectivity over related lipoxygenases and cyclooxygenases, and possesses favorable ADME properties.

Availability: In stock

Package Price Qty
5 mg
$110.00
10 mg
$180.00
50 mg
$750.00
100 mg
$1,150.00
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Biological Activity

ML355 is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 μM, shows excellent selectivity over related lipoxygenases and cyclooxygenases, and possesses favorable ADME properties.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.49 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.26 mL 11.32 mL 22.65 mL
5 mM 0.45 mL 2.26 mL 4.53 mL

*The above data is based on the productmolecular weight 441.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18349
Actions Inhibitor
M. Wt 441.52
Formula C21H19N3O4S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1532593-30-8
Synonyms ML 355, ML-355
SMILES O=S(C1=CC=C(NCC2=CC=CC(OC)=C2O)C=C1)(NC3=NC4=CC=CC=C4S3)=O

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