ML355

Catalog No.: A18349
12-Lipoxygenase (12-LOX) inhibitor
ML355 is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 μM, shows excellent selectivity over related lipoxygenases and cyclooxygenases, and possesses favorable ADME properties.
Grouped product items
Product Name Price Stock Qty
ML355 5mg
$110.00
In stock
ML355 10mg
$180.00
In stock
ML355 50mg
$750.00
In stock
ML355 100mg
$1,150.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription ML355 is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 μM, shows excellent selectivity over related lipoxygenases and cyclooxygenases, and possesses favorable ADME properties.
Targets
Target Value
Product Information
Catalog Num A18349
Formula C21H19N3O4S2
Molecular Weight 441.52
CAS Number 1532593-30-8
SMILES O=S(C1=CC=C(NCC2=CC=CC(OC)=C2O)C=C1)(NC3=NC4=CC=CC=C4S3)=O
Synonyms ML 355, ML-355
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 86 mg/mL (194.78 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.49 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.26 mL 11.32 mL 22.65 mL
5 mM 0.45 mL 2.26 mL 4.53 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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