MLCK Inhibitor Peptide 18 is a selective inhibitor of myosin light chain kinase (MLCK) with an IC50 of 50 nM. This peptide demonstrates significant inhibition of MLCK activity while exhibiting minimal effects on Ca2+/calmodulin-dependent protein kinase II, requiring concentrations approximately 4000-fold higher for inhibition. This specificity makes it valuable for studying MLCK-related signaling pathways and cellular processes involving muscle contraction and cellular motility.
MLCK Inhibitor Peptide 18 is a selective inhibitor of myosin light chain kinase (MLCK) with an IC50 of 50 nM. This peptide demonstrates significant inhibition of MLCK activity while exhibiting minimal effects on Ca2+/calmodulin-dependent protein kinase II, requiring concentrations approximately 4000-fold higher for inhibition. This specificity makes it valuable for studying MLCK-related signaling pathways and cellular processes involving muscle contraction and cellular motility.
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