MLGFFQQPKPR-NH2

Catalog No.: A62053
Reversed Substance P
MLGFFQQPKPR-NH2 is a reversed Substance P peptide that acts as an antagonist to its neuropeptide target. This compound has demonstrated the ability to interfere with neurogenic inflammation and modulate pain response, making it a valuable tool for studies of nociception and neuropeptide signaling. Research applications include investigations into pain mechanisms and the development of potential therapeutic strategies for pain management.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMLGFFQQPKPR-NH2 is a reversed Substance P peptide that acts as an antagonist to its neuropeptide target. This compound has demonstrated the ability to interfere with neurogenic inflammation and modulate pain response, making it a valuable tool for studies of nociception and neuropeptide signaling. Research applications include investigations into pain mechanisms and the development of potential therapeutic strategies for pain management.
Product Information
Catalog NumA62053
FormulaC63H98N18O13S
Molecular Weight1347.63
CAS Number1802883-75-5
Sequence shorteningMLGFFQQPKPR-NH2
SMILESCSCC[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
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