Fig. 1 · Structure
Documents & Downloads
MLK-IN-2
MLK3 Inhibitor
MLK-IN-2 is a potent inhibitor of Mixed Lineage Kinase 3 (MLK3) with an IC50 value of 6 nM. This small molecule features a 3H-imidazole [4,5-b] pyridine structure, making it a valuable tool for investigating the role of MLK3 in various biological processes. MLK-IN-2 is primarily used in research related to cancer and neurodegenerative diseases, facilitating the elucidation of therapeutic targets and mechanisms of action.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2614255-51-3 |
| Applications | MLK3 Inhibitor |
| Formula | C29H34BrN7O4S |
| Molecular Weight | 656.59 |
| SMILES | O=C(N1CCOCC1)C2=CC=CC(N3C(C)=C(C4=NC(C(N[C@H]5CCN(S(CC)(=O)=O)C5)=C(Br)C=N6)=C6N4)C=C3C)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.