MLK

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Catalog No.
Product Name
Application
Product Information
Product Citation
  1. MLKL inhibitor

    TC13172 is a mixed lineage kinase domain-like protein (MLKL) inhibitor with an EC50 value of 2 nM for HT-29 cells.
  2. MLK inhibitor

    URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively.
  3. MLKL inhibitor

    Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29.
  4. DLK inhibitor

    GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK).
  5. MLKL inhibitor

    GW806742X is a Mixed Lineage Kinase Domain-Like protein (MLKL) inhibitor which binds the MLKL pseudokinase domain with a Kd value of 9.3 μM and has anti-necroptosis activity. GW806742X has activity against VEGFR2.

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