MLN2238 (Ixazomib)

Catalog No.: A10600
Proteasome Inhibitor
MLN2238 is a potent reversible and specific β5 site of the 20S proteasome inhibitor with an IC50 value of 3.4 nM.
Grouped product items
Product Name Price Stock Qty
MLN2238 5mg
$90.00
In stock
MLN2238 10mg
$120.00
In stock
MLN2238 50mg
$350.00
In stock
MLN2238 100mg
$600.00
In stock
MLN2238 10mM * 1mL in DMSO
$90.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription MLN2238 is a potent reversible and specific β5 site of the 20S proteasome inhibitor with an IC50 value of 3.4 nM.
Targets
Target Value
Product Information
Catalog Num A10600
Formula C14H19BCl2N2O4
Molecular Weight 361
CAS Number 1072833-77-2
SMILES B([C@H](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 64 mg/mL (177.26 mM)
Water Insoluble
Ethanol 8 mg/mL (22.15 mM)
In vivo 5% DMSO+45% PEG 300+ddH2O 16 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.7 mL 138.5 mL 277.01 mL
0.5 mM 5.54 mL 27.7 mL 55.4 mL
1 mM 2.77 mL 13.85 mL 27.7 mL
5 mM 0.55 mL 2.77 mL 5.54 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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