Fig. 1 · Structure

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MLS000099089

Cat. No. A76470 CAS 423735-70-0

12/15-LOX Inhibitor

MLS000099089 is a potent inhibitor of 12/15-lipoxygenase (12/15-LOX), demonstrating IC50 values of 3.4 μM for human and 10 μM for murine 12/15-LOX. This compound exhibits notable selectivity for 12/15-LOX over 5-LOX and COX-2, making it a valuable tool for research. MLS000099089 is applicable in studies related to stroke and other pathophysiological conditions involving lipoxygenase pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 423735-70-0
Applications 12/15-LOX Inhibitor
Formula C17H16N2O
Molecular Weight 264.32
SMILES
OC1=C(C2=NNC(C3=C(C)C=CC=C3)=C2)C=C(C)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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