Fig. 1 · Structure
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MLS000536924
Cat. No.
A76467
CAS
511306-37-9
Lipoxygenase Inhibitor
MLS000536924 is a selective inhibitor of human epithelial 15-lipoxygenase-2, exhibiting competitive inhibition with over 50-fold selectivity. This compound plays a crucial role in exploring the biological functions of h15-LOX-2 and is particularly relevant in research areas including atherosclerosis, cystic fibrosis, and ferroptosis. The binding mechanism of MLS000536924 demonstrates significant restriction of protein mobility, confirming its enhanced biological efficacy compared to other lipoxygenase inhibitors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 511306-37-9 |
| Applications | Lipoxygenase Inhibitor |
| Formula | C16H15N3S |
| Molecular Weight | 281.38 |
| SMILES | CC1=CC=C(C=C1)CSC2=NN(C=N2)C3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.