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MMP-2/MMP-9 Substrate

MMP-2/MMP-9 Substrate is a synthetic chromogenic polypeptide designed to mimic the cleavage sites of matrix metalloproteinases 2 and 9, also known as gelatinases A and B, within collagen. Upon hydrolysis by collagenase, this substrate interacts with 4,4'-dithiodipyridine or Ellman's Reagent through its thiol group, resulting in a detectable product with distinct ultraviolet absorption characteristics. It is a valuable tool for studying MMP activity and has applications in research related to tissue remodeling, cancer metastasis, and inflammatory processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	99828-55-4
Applications	MMP-2/MMP-9 Substrate
Formula	C₃₁H₅₃N₅O₈S
Molecular Weight	655.85
Synonyms	Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
SMILES	C(N[C@H](C(NCC(S[C@H](C(N[C@H](C(NCC(OCC)=O)=O)CC(C)C)=O)CC(C)C)=O)=O)CC(C)C)(=O)[C@H]1N(C(C)=O)CCC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.