Fig. 1 · Structure

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MMP-9-IN-8

MMP-9 Inhibitor

MMP-9-IN-8 is a selective matrix metalloproteinase-9 (MMP-9) inhibitor that exhibits inhibitory activities of 42.16% and 58.28% at concentrations of 10 μM and 50 μM, respectively. This compound demonstrates notable anti-cancer properties, effectively inducing apoptosis in MCF-7 breast cancer cells, with an IC50 value of 23.42 μM. MMP-9-IN-8 is suitable for research applications involving cancer biology and therapeutic development targeting tumor progression and metastasis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2490543-89-8
Applications MMP-9 Inhibitor
Formula C20H21F4N7O
Molecular Weight 451.42
SMILES
O=C(NC1=CC=C(C(C(F)(F)F)=C1)F)NC2=NC(N3CCN(CC3)C)=C(C=CN4C)C4=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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