Fig. 1 · Structure
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MMP12-IN-3
MMP12 Inhibitor
MMP12-IN-3 is a potent inhibitor of matrix metalloproteinase 12 (MMP12), exhibiting an IC50 value of 4.9 nM. This compound is relevant for research into chronic respiratory diseases, particularly emphysema, due to its role in modulating extracellular matrix remodeling and inflammation. Its specificity and efficacy make it a valuable tool for exploring therapeutic strategies targeting MMP12 in pulmonary pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 208663-26-7 |
| Applications | MMP12 Inhibitor |
| Formula | C20H26N2O5S |
| Molecular Weight | 406.50 |
| SMILES | CC(C)CC(N(S(=O)(C1=CC=C(OC)C=C1)=O)CC2=CC=CC=C2)C(NO)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.