Fig. 1 · Structure

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MMP13-IN-4

MMP-13 Inhibitor

MMP13-IN-4 is a selective inhibitor of matrix metalloproteinase-13 (MMP-13) with an IC50 of 14.6 μM. This compound demonstrates significant activity in modulating the enzymatic activity associated with osteoarthritis (OA). MMP13-IN-4 is a valuable tool for research focused on understanding the role of MMP-13 in pathological conditions and developing therapeutic strategies for osteoarthritis.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 514855-02-8
Applications MMP-13 Inhibitor
Formula C21H17BrN4O5
Molecular Weight 485.29
SMILES
O=C(N/N=C(C1=CC=C(NC(C2=CC=C(Br)O2)=O)C=C1)\C)CC3=CC=C([N+]([O-])=O)C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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