MMPIP hydrochloride is a selective allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) with KB values ranging from 24 to 30 nM. It serves as a valuable pharmacological tool for investigating the role of mGluR7 in central nervous system functions. Research indicates that MMPIP hydrochloride can alleviate pain and restore normative affective and cognitive behaviors in models of neuropathic pain.
MMPIP hydrochloride is a selective allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) with KB values ranging from 24 to 30 nM. It serves as a valuable pharmacological tool for investigating the role of mGluR7 in central nervous system functions. Research indicates that MMPIP hydrochloride can alleviate pain and restore normative affective and cognitive behaviors in models of neuropathic pain.
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