MMPIP is a selective allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7) with a high affinity (KB values of 24-30 nM). This compound serves as a valuable tool for investigating the role of mGluR7 in central nervous system functions. Research demonstrates that MMPIP can alleviate pain and restore cognitive and affective behaviors in models of neuropathic pain, making it significant for studies in neuropharmacology and mental health.
MMPIP is a selective allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7) with a high affinity (KB values of 24-30 nM). This compound serves as a valuable tool for investigating the role of mGluR7 in central nervous system functions. Research demonstrates that MMPIP can alleviate pain and restore cognitive and affective behaviors in models of neuropathic pain, making it significant for studies in neuropharmacology and mental health.
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