Fig. 1 · Structure
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MMV665916
Antimalarial Agent
MMV665916 is a quinazolinedione derivative that acts as an antimalarial agent. It exhibits potent antiplasmodial activity against the Plasmodium falciparum FcB1 strain, demonstrating an effective EC50 of 0.4 μM, coupled with a high selectivity index (SI>250). This compound is suitable for research applications aimed at understanding malaria biology and developing novel therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 896356-25-5 |
| Applications | Antimalarial Agent |
| Formula | C19H19N3O4 |
| Molecular Weight | 353.37 |
| SMILES | O=C1N(CCC(NCC2=CC=CC=C2OC)=O)C(C3=CC=CC=C3N1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.