Fig. 1 · Structure
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MMV666693
Plasmodium Translation Inhibitor
MMV666693 is a translation inhibitor that selectively targets Plasmodium falciparum. This compound exhibits low cytotoxicity in human fibroblasts, with an IC50 greater than 32 µM, making it a promising candidate for antimalarial drug development. Its ability to interfere with protein synthesis in the parasite underscores its potential for further research in treating malaria.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 312527-99-4 |
| Applications | Plasmodium Translation Inhibitor |
| Formula | C18H15NO4 |
| Molecular Weight | 309.32 |
| SMILES | O=C1N=C(OC2=CC=CC=C12)/C=C/C3=CC=CC(OC)=C3OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.