Fig. 1 · Structure
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MMV667492
Cat. No.
A73287
CAS
380877-02-1
Endogenous Metabolite
MMV667492 is a potent inhibitor of the cytoskeletal protein Ezrin, effectively targeting its function in cellular processes. This compound demonstrates significant anti-invasion activity in osteosarcoma cells, hindering their metastatic potential. In addition to its in vitro efficacy, MMV667492 induces distinct morphological defects in zebrafish embryos, aligning with Ezrin inhibition mechanisms. Furthermore, it reduces lung metastasis in osteosarcoma models characterized by elevated Ezrin expression, making it a valuable tool for studying tumor biology and metastasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 380877-02-1 |
| Applications | Endogenous Metabolite |
| Formula | C17H19N3O3 |
| Molecular Weight | 313.35 |
| SMILES | O=C1C(NC2CCCCC2)=C(N(C)N=O)C(C3=C1C=CC=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.