Fig. 1 · Structure

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MMV688533

antimalarial agent

MMV688533 is an antimalarial agent that targets and inhibits asexual blood stage parasites of Plasmodium falciparum, demonstrating significant anti-plasmodial activity with an IC50 of 1.3 nM. This compound is effective in single-dose applications in humanized mouse models, showcasing rapid action against malaria infections. Additionally, MMV688533 displays favorable pharmacokinetic properties and a strong safety profile, making it a valuable tool for malaria research and therapeutic development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2260904-47-8
Applications antimalarial agent
Formula C24H15F6N5O2
Molecular Weight 519.40
SMILES
O=C(C1=CC(C#CC2=CC=C(C(F)(F)F)C(C(NC3=NC=CC=C3)=O)=C2)=CC(C(F)(F)F)=C1)NC(N)=N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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