Fig. 1 · Structure
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MMV688844
DNA Gyrase Inhibitor
MMV688844 is a potent inhibitor of DNA gyrase, specifically targeting Mycobacterium abscessus. With an IC50 value of 2 μM, it demonstrates significant bactericidal activity, exhibiting a MIC50 of 12 μM against Mabs bamboo. This compound is valuable for research focused on antibacterial mechanisms and the treatment of mycobacterial infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2650213-59-3 |
| Applications | DNA Gyrase Inhibitor |
| Formula | C23H25ClN4O2 |
| Molecular Weight | 424.92 |
| SMILES | O=C(C1CCN(CCC2=CC=C(Cl)C=C2)CC1)NC3=CC=NC4=CC=C(OC)N=C34 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.