Momelotinib Mesylate

Catalog No.: A21658

JAK1/JAK2 inhibitor

Momelotinib Mesylate

Momelotinib Mesylate Chemical Structure

CAS NO. 1056636-07-7

Momelotinib Mesylate (CYT387 Mesylate) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, appr 10-fold selectivity versus JAK3.

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1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Momelotinib Mesylate (CYT387 Mesylate) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, appr 10-fold selectivity versus JAK3.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.59 mL 97.93 mL 195.86 mL
0.5 mM 3.92 mL 19.59 mL 39.17 mL
1 mM 1.96 mL 9.79 mL 19.59 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 510.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21658
Actions Inhibitor
M. Wt 510.57
Formula C24H26N6O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1056636-07-7
Synonyms CYT387 (Mesylate), CYT 387, CYT-387
SMILES O=C(C1=CC=C(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)C=C1)NCC#N.O=S(O)(C)=O

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