Momordicoside G

Catalog No.: A32828
Apoptosis Inducer
Momordicoside G is a cucurbitane-type triterpene glycoside that functions as an apoptosis inducer. It selectively triggers apoptosis in M1-like macrophages while sparing M2-like macrophages, thereby modulating immune responses. Additionally, Momordicoside G reduces intracellular reactive oxygen species (ROS) and promotes autophagy, contributing to its anticancer properties by inhibiting the growth of various cancer cell lines. Furthermore, it stimulates repair mechanisms in M2-associated lung injury and provides protective effects against inflammatory lung cancer damage.
Grouped product items
Size Price Stock Qty
5mg
$605.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMomordicoside G is a cucurbitane-type triterpene glycoside that functions as an apoptosis inducer. It selectively triggers apoptosis in M1-like macrophages while sparing M2-like macrophages, thereby modulating immune responses. Additionally, Momordicoside G reduces intracellular reactive oxygen species (ROS) and promotes autophagy, contributing to its anticancer properties by inhibiting the growth of various cancer cell lines. Furthermore, it stimulates repair mechanisms in M2-associated lung injury and provides protective effects against inflammatory lung cancer damage.
Product Information
Catalog NumA32828
FormulaC37H60O8
Molecular Weight632.87
CAS Number81371-54-2
SMILESC[C@]12[C@@]3([H])[C@@]4(CC[C@@]1([C@]([C@H](C)C/C=C/C(C)(C)OC)([H])CC2)C)[C@@]5([H])[C@@](OC4)(C(C)([C@@H](O[C@]6([H])O[C@@H]([C@@H](O)[C@@H](O)[C@H]6O)CO)CC5)C)C=C3
SynonymsMomordicacoside G
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