Fig. 1 · Structure
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Monomethyl auristatin E intermediate-14
Intermediate Reactant
Monomethyl auristatin E intermediate-14 is a crucial intermediate reagent in the synthesis of Monomethyl auristatin E (MMAE), a microtubule and tubulin inhibitor with potent anticancer properties. MMAE is commonly utilized as the cytotoxic agent in antibody-drug conjugates (ADCs), facilitating targeted cancer therapy. This intermediate is essential for researchers developing novel ADC therapies aimed at improving treatment outcomes in oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1932791-56-4 |
| Applications | Intermediate Reactant |
| Formula | C13H19NO2 |
| Molecular Weight | 221.30 |
| SMILES | CC[C@H](C)[C@H](C(O)=O)NCC1=CC=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.