Monomethyl auristatin F (MMAF)

Catalog No.: A13955
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A.
Grouped product items
Product Name Price Stock Qty
MonoMethylauristatin F (MMAF) 2mg
$170.00
In stock
MonoMethylauristatin F (MMAF) 5mg
$320.00
In stock
MonoMethylauristatin F (MMAF) 10mg
$480.00
In stock
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Biological Activity
Discription Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A.
Targets
Target Value
Product Information
Catalog Num A13955
Formula C39H65N5O8
Molecular Weight 731.98
CAS Number 745017-94-1
SMILES O=C(N2[C@H]([C@H](OC)[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)C)CCC2)C[C@@H](OC)[C@@H](N(C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C)C)[C@@H](C)CC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 87 mg/mL (118.85 mM)
Water 87 mg/mL (118.85 mM)
Ethanol 87 mg/mL (118.85 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.66 mL 68.31 mL 136.62 mL
0.5 mM 2.73 mL 13.66 mL 27.32 mL
1 mM 1.37 mL 6.83 mL 13.66 mL
5 mM 0.27 mL 1.37 mL 2.73 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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