Biological Activity
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 13.66 mL | 68.31 mL | 136.62 mL |
0.5 mM | 2.73 mL | 13.66 mL | 27.32 mL |
1 mM | 1.37 mL | 6.83 mL | 13.66 mL |
5 mM | 0.27 mL | 1.37 mL | 2.73 mL |
*The above data is based on the productmolecular weight 731.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13955 |
---|---|
M. Wt | 731.98 |
Formula | C39H65N5O8 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 745017-94-1 |
Synonyms | 0 |
SMILES | O=C(N2[[email protected]]([[email protected]](OC)[[email protected]](C(=O)N[[email protected]](C(=O)O)Cc1ccccc1)C)CCC2)C[[email protected]@H](OC)[[email protected]@H](N(C(=O)[[email protected]@H](NC(=O)[[email protected]@H](NC)C(C)C)C(C)C)C)[[email protected]@H](C)CC |
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