Fig. 1 · Structure
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Mosliciguat
Guanylate Cyclase Activator
Mosliciguat is a potent guanylate cyclase activator that enhances nitric oxide signaling through the stimulation of soluble guanylate cyclase. This compound exhibits key biological activities, including vasodilation and reduced blood pressure, making it relevant for cardiovascular research. Mosliciguat is primarily utilized in studies assessing pulmonary hypertension and related disorders, providing valuable insights into endothelial function and smooth muscle relaxation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2231749-54-3 |
| Applications | Guanylate Cyclase Activator |
| Formula | C41H36ClF3N2O5 |
| Molecular Weight | 729.18 |
| Synonyms | BAY 1237592 |
| SMILES | OC(C1=CC=C(C2=N1)[C@H](CCC2)N(CCC(C=C3)=CC=C3C(O)=O)CCC(C=CC=C4)=C4OCC(C=CC(C(C=C5)=CC=C5C(F)(F)F)=C6)=C6Cl)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.