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mPGES1-IN-3

Catalog No.: A20454
mPGES-1 inhibitor
mPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor, which exhibits excellent mPGES-1 enzyme (IC50: 8 nM), cell (A549 IC50: 16.24 nM) and human whole blood potency (IC50: 249.9 nM).
mPGES1-IN-3
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Product Name Price Stock Qty
mPGES1-IN-3 1mg
$320.00
In stock
mPGES1-IN-3 5mg
$960.00
In stock
mPGES1-IN-3 10mg
$1,600.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription mPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor, which exhibits excellent mPGES-1 enzyme (IC50: 8 nM), cell (A549 IC50: 16.24 nM) and human whole blood potency (IC50: 249.9 nM).
Product Information
Catalog Num A20454
Formula C24H16ClF5N4O3
Molecular Weight 538.85
CAS Number 1469976-70-2
SMILES O=C(NC1=CC(F)=CC(C(F)(F)F)=C1)C2=C(OCCO3)C3=C(N(C)C(NC4=C(Cl)C=CC=C4F)=N5)C5=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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Immunology & Inflammation > PGE Synthase
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