Fig. 1 · Structure
Documents & Downloads
Mpro/PLpro-IN-1
Mpro/PLpro Inhibitor
Mpro/PLpro-IN-1 is a dual inhibitor targeting the main protease (Mpro) and papain-like protease (PLpro) of SARS-CoV-2. It demonstrates notable biological activity with a micromolar inhibitory potency against Mpro (IC50 = 1.72 μM) and submicromolar potency against PLpro (IC50 = 0.67 μM). This compound is valuable for research applications focused on the development of antiviral therapies for COVID-19 by disrupting essential viral protease functions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2766185-78-6 |
| Applications | Mpro/PLpro Inhibitor |
| Formula | C25H27ClN4O3 |
| Molecular Weight | 466.96 |
| SMILES | C=CC[C@H](NC(CCl)=O)C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(NCC3=CC=CC=C3)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.