Fig. 1 · Structure
Documents & Downloads
Mps1-IN-1 dihydrochloride
Mps1 Inhibitor
Mps1-IN-1 dihydrochloride is a potent ATP-competitive inhibitor of Mps1 kinase, exhibiting an IC50 of 367 nM. This compound effectively inhibits Mps1 mitotic kinase activity, disrupting spindle assembly checkpoint (SAC) function and leading to compromised cell cycle regulation. Mps1-IN-1 dihydrochloride demonstrates cytotoxic effects in various cellular contexts, impacting both cancerous and normal cells, making it a valuable tool for research in cell division and cancer therapy.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1883548-93-3 |
| Applications | Mps1 Inhibitor |
| Formula | C28H35Cl2N5O4S |
| Molecular Weight | 608.58 |
| SMILES | OC1CCN(C2=CC=C(NC3=CC(NC4=CC=CC=C4S(=O)(C(C)C)=O)=C5C(NC=C5)=N3)C(OC)=C2)CC1.[H]Cl.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.