Target & Activity
| Target | Activity | Value |
|---|---|---|
| HDAC1 | IC50 | 53.0 nM |
| HDAC2 | IC50 | 106.2 nM |
| HDAC6 | IC50 | 29.5 nM |
| HDAC8 | IC50 | 2532.6 nM |
Fig. 1 · Structure
Documents & Downloads
Imofinostat (MPT0E028)
Cat. No.
A18982
CAS
1338320-94-7
HDAC inhibitor
MPT0E028 is an orally active and selective HDAC inhibitor with IC50s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2 and HDAC6, respectively.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1338320-94-7 |
| Applications | HDAC inhibitor |
| Formula | C17H16N2O4S |
| Molecular Weight | 344.38 |
| Synonyms | MPT-0E028 |
| SMILES | O=C(/C=C/C1=CC2=C(C=C1)N(CC2)S(=O)(C3=CC=CC=C3)=O)NO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.