MR-16728 hydrochloride

Catalog No.: A73346
Endogenous Metabolite
MR-16728 hydrochloride is an endogenous metabolite that primarily promotes the release of acetylcholine through inhibition of Ca(2+)-ATPase activity in presynaptic membranes. It effectively enhances acetylcholine release and demonstrates significant activity in the presence of low calcium concentrations. Research applications include studying neurotransmitter release mechanisms and analyzing acetylcholine dynamics under various physiological conditions. The compound shows a half-maximal effect at a concentration of 13.5 μM, making it a valuable tool for investigating synaptic transmission and neuromodulation.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMR-16728 hydrochloride is an endogenous metabolite that primarily promotes the release of acetylcholine through inhibition of Ca(2+)-ATPase activity in presynaptic membranes. It effectively enhances acetylcholine release and demonstrates significant activity in the presence of low calcium concentrations. Research applications include studying neurotransmitter release mechanisms and analyzing acetylcholine dynamics under various physiological conditions. The compound shows a half-maximal effect at a concentration of 13.5 μM, making it a valuable tool for investigating synaptic transmission and neuromodulation.
Product Information
Catalog NumA73346
FormulaC23H37ClN2O
Molecular Weight393.01
CAS Number207403-36-9
SMILESO=C(NCCCN1CCCCCC1)C(C2CCCCC2)C3=CC=CC=C3.Cl
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