MRL-1237

Catalog No.: A50832
Enteroviruses Replication Inhibitor
MRL-1237 is an enterovirus replication inhibitor that targets the non-structural protein 2C. It demonstrates effective inhibition of poliovirus and other enteroviruses, making it a valuable tool for studying viral infections. Notably, MRL-1237 does not interfere with the NTPase (ATPase) activity of the 2C protein, allowing for specific mechanistic investigations in enteroviral research applications.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMRL-1237 is an enterovirus replication inhibitor that targets the non-structural protein 2C. It demonstrates effective inhibition of poliovirus and other enteroviruses, making it a valuable tool for studying viral infections. Notably, MRL-1237 does not interfere with the NTPase (ATPase) activity of the 2C protein, allowing for specific mechanistic investigations in enteroviral research applications.
Product Information
Catalog NumA50832
FormulaC19H16ClFN4
Molecular Weight354.81
CAS Number276704-21-3
SMILESN=C1C=CN(CC2=NC3=CC=CC=C3N2C4=CC=C(F)C=C4)C=C1.Cl
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