MRL828

Catalog No.: A39669
Tau ATTEC
MRL828 is a Tau pathology-binding compound that employs the ATTEC technology to selectively target aggregated tau proteins for degradation via the autophagic lysosomal pathway. This reagent effectively decreases intracellular tau aggregates while promoting the secretion of tau from cells. Its unique mechanism makes MRL828 a valuable tool for research on tau-related pathologies and neurodegenerative diseases.
Grouped product items
Size Price Stock Qty
5mg
$1,365.00
In stock
10mg
$2,100.00
In stock
25mg
$3,780.00
In stock
50mg
$5,535.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMRL828 is a Tau pathology-binding compound that employs the ATTEC technology to selectively target aggregated tau proteins for degradation via the autophagic lysosomal pathway. This reagent effectively decreases intracellular tau aggregates while promoting the secretion of tau from cells. Its unique mechanism makes MRL828 a valuable tool for research on tau-related pathologies and neurodegenerative diseases.
Product Information
Catalog NumA39669
FormulaC46H51FN14O5S
Molecular Weight931.05
CAS Number3115333-82-6
SMILESO=C(NCCCOCCCCOCCCNC1=NC=C(C#CC2=CC=C(C3=CN4C=C(CO)C=CC4=N3)N=C2)C=N1)[C@@H](NC(C)=O)CSC5=NC6=C(N)N=C(N)N=C6N5CC7=CC=C(F)C=C7
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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