Fig. 1 · Structure
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MRTX849 analog 24
MRTX849 Probe
MRTX849 analog 24 is an alkyne-containing click probe designed to target KRAS G12C. This compound serves as a valuable tool for investigating the biological function and pharmacological properties of MRTX849. It is applicable in research focused on KRAS-related signaling pathways and therapeutic strategies for cancers driven by KRAS mutations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2490716-96-4 |
| Applications | MRTX849 Probe |
| Formula | C36H39ClFN7O2 |
| Molecular Weight | 656.19 |
| SMILES | N#CC[C@@H]1N(C(C(F)=C)=O)CCN(C2=C3C(CN(C4=C5C(Cl)=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(CCCC#C)CCC6)=N2)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.