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MS-PEG12-THP

PROTAC Linkers

MS-PEG12-THP is a polyethylene glycol (PEG)-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the efficient conjugation of target proteins to E3 ubiquitin ligases, thereby enhancing the degradation of specific proteins in cellular contexts. Its applications include drug development and the study of targeted protein degradation mechanisms, making it a valuable tool in chemical biology and therapeutic research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	552886-58-5
Applications	PROTAC Linkers
Formula	C₃₀H₆₀O₁₆S
Molecular Weight	708.85
SMILES	O=S(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC1CCCCO1)(C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.